The Toyota Prius is a full hybrid electric mid-size car developed and manufactured by the Toyota Motor Corporation. It first went on sale in Japan in 1997, making it the first mass-produced hybrid vehicle. It was subsequently introduced worldwide in 2001. The Prius is sold in more than 40 countries and regions, with its largest markets being those of Japan and North America.

Brian's car has been specifically identified as a 2004 Toyota Prius in the DVD commentaries. The license plate normally reads "BRI-D0G" and it has a 'Kucinich 04' bumper sticker. In a DVD-exclusive scene in The Former Life of Brian, Brian did change the license plate to read 'DYLANS DAD'. It's early appearances show it in the same cartoonish animation, but is currently rendered in more realistic form.