During one scene Lois helps Peter remember how to have intercourse but it gets cut off by the FCC for censorship reasons, they then have Dwayne Johnson simulate the scene in which he has a Peter action figure banging against a Lois action figure. Johnson was appearing to promote his movie Tooth Fairy, which co-stars Family Guy creator Seth MacFarlane.
The action figures Dwayne Johnson uses are the official ones made by Mezco.
This is the second time Meg is thrown out the kitchen by making a sexual joke about one of her parents. The first time was about Lois in "Model Misbehavior" this time she makes one about wanting to have sex with Peter.
The [adult swim] commercial bumpers are parodied at the end of the first act. When this episode actually aired on [adult swim], Cartoon Network returned the favor by replacing their normal commercial bumpers with parodies of Fox's Animation Domination promos, reading "You're watching Fox! But not that Fox. The Fox for people who watch Fox on [adult swim]. So remember, that's Fox on [adult swim] on Cartoon Network....on Fox."
Peter insinuates he had sex with Tiffany Amber Thiessen from Saved by the Bell. In real life, Tiffani was indeed pregnant, and gave birth to a daughter in June 2010.
The uncensored version includes a scene where Stewie swears at a black man from the low-rent apartment.
Lois tells Peter to play Grand Theft Auto in order to practice driving. Eight hours later he is seen beating up a hooker with a baseball bat and stealing a car, much like the related activities in the real game. It should also be noted that Peter is playing the game on the Xbox 360, but this doesn't mean that he was playing the 4th installment in the series which was the first one issued for the Xbox 360; the box art that is seen indicates that he may have been playing Grand Theft Auto III.
Peter is seen playing an Xbox 360 here but in "April in Quahog" the console is first purchased.