Daniel Palladino is one of the producers of the American animated sitcom Family Guy. Palladino is also a former producer, writer, and director for the American dramedy Gilmore Girls and he executive produced The Return of Jezebel James. He is married to television writer and producer Amy Sherman-Palladino, the creator of Gilmore Girls and The Return of Jezebel James.

He executive produced or co-excutive produced the episodes "Road to Rhode Island", "Dammit Janet!", "He's Too Sexy for His Fat", "E. Peterbus Unum", "The Story on Page One", "Wasted Talent", "Fore Father", "The Thin White Line", "Brian Does Hollywood" , "Mr. Griffin Goes to Washington", "One if by Clam, Two if by Sea", "And the Wiener is...", "Death Lives", "Lethal Weapons", "The Kiss Seen Around the World", "Mr. Saturday Knight", "A Fish out of Water", "Emission Impossible", "To Love and Die in Dixie", "Screwed the Pooch", "Peter Griffin: Husband, Father...Brother?", "Ready, Willing, and Disabled", "Brian Wallows and Peter's Swallows" , "From Method to Madness", "Stuck Together, Torn Apart", and "Family Guy Viewer Mail".

Not only did he executive produce "Road to Europe", but he also wrote the episode. He is also credited as the writer of "Valentine's Day in Quahog".