Danny Trejo is an actor known for his work in From Dusk Till Dawn, the Spy Kids films and the Machete series.

Danny appears as himself in a cutaway gag in "Dog Bites Bear" when Meg notes that Peter and Lois have a weird but strong relationship, like Danny. Later, the voiceover from Vin Diesel on Stewie's The Fast and the Furious DVD set notes that a friend that kills another friend is not strong and Danny Trejo is strong.