Donna Tubbs-Brown is Cleveland Brown's second wife, after his first wife Loretta had an affair with one of Cleveland's old friends, Glenn Quagmire, causing them to divorce. She works as the principal's assistant at Stoolbend High School. She has two children from her previous marriage to Robert Tubbs, named Roberta and Rallo. As a result of her marriage to Cleveland, she has gained a stepson Cleveland Brown, Jr..

She appears in "The Splendid Source", having dinner with Cleveland's old friends. She still wants a real wedding gift. The Griffins, Swansons, and Quagmire had attended Cleveland and Donna's wedding in the pilot of The Cleveland Show.

She is mentioned on her husband's record-your-own-message birthday card for Peter Griffin in "Baby, You Knock Me Out".

Donna appears in "Cool Hand Peter" when Lois Griffin and the girls cut loose while the guys go on a road trip.

She is voiced by Sanaa Lathan.

For more information, see Donna's page on The Cleveland Show Wiki.