- This episode marks the first time in Family Guy where animation directors are credited as writers.
- Peter changes the name on Meg's birth certificate to "Megatron", even though most characters call her "Megan". It also doesn't feature Meg's middle name.
- In "Inside Family Guy", the hallways of the production offices feature props from past episodes including the Megatron birth certificate.
- This is the first episode to contradict Quagmire's established age of 61 as his encounter with Tracey Bellings as a youth is set in 1986. However, he is clearly an older adult by 1988 in "Meet the Quagmires".
- Stewie imagines a Menstrual Cycle as a creation inspired by Dr. Seuss. Meg later rides off on just such a device.
- Meg's sex tape video displays "1 views", instead of "1 view".
- When Meg opens her locker, it's shown that she has a child, which she keeps locked in there.
- This is the second time Brian has been shaved after "Breaking Out is Hard to Do" in which Peter sets up a cutaway poking fun at swimmer Greg Louganis.
- It is revealed that Patty has two lesbian mothers.
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| << Season 11 | Family Guy Season 12 | Season 13 >> | |||||||||
| #01 | Finders Keepers | #08 | Christmas Guy | #15 | Secondhand Spoke | ||||||
| #02 | Vestigial Peter | #09 | Peter Problems | #16 | Herpe, the Love Sore | ||||||
| #03 | Quagmire's Quagmire | #10 | Grimm Job | #17 | The Most Interesting Man in the World | ||||||
| #04 | A Fistful of Meg | #11 | Brian's a Bad Father | #18 | Baby Got Black | ||||||
| #05 | Boopa-Dee Bappa-Dee | #12 | Mom's the Word | #19 | Meg Stinks! | ||||||
| #06 | Life of Brian | #13 | 3 Acts of God | #20 | He's Bla-ack! | ||||||
| #07 | In Harmony's Way | #14 | Fresh Heir | #21 | Chap Stewie | ||||||