At the beginning of the episode, there is a play that Lois and Brian attend starring Mark Hentemann, based on the name of a writer on the show.
The music played during Stewie's sexy parties is Burt Bacharach's "Bond Street".
In the car after meeting the nudists, Chris can’t stop saying “Boobies!”, so Lois uses a Neuralizer from Men in Black and makes Chris believe he just came back from the circus.
Stewie warns Olivia that she might “get booted out of here and end up like Linda Evans.” Evans is then paged while working in a supermarket.
After a solo performance, an angry audience member describes Stewie’s show as being worse than Seussical, a Broadway show that opened in November 2000 and was panned by the critics.
When Stewie is giving a press conference to his stuffed toys, he mentions advice given to him by filmmaker Martin Scorsese and his part across from Chris O’Donnell.
When Olivia visits Stewie one last time, he claims to have a guest role on an upcoming episode of Gilmore Girls. Seth MacFarlane performed recurring guest roles on the show.
To illustrate Peter’s concern about child acting, a cutaway features Elroy Jetson, a character from televised cartoon The Jetsons who, as an adult, is kicked out of a pub bruised and drunken. It goes on to show grown up Bam-Bam, the child from The Flintstones has now become a taxicab driver.
When Stewie and Olivia are arguing about which one of them was off on the F#, the note they are humming is actually a G, not an F sharp.
Bamm-Bamm Rubble is drawn with whites in his eyes, his eyes are drawn with Flesh-toned or Black. The same thing is done in "The Cleveland-Loretta Quagmire".
During Stewie's Life Cycle exercise, Simon instructs Stewie to "burst through the placenta". This should have been a term like "birth canal" instead of placenta. The placenta is an organ that provides the fetus with food and removes waste, not something that the fetus passes through during birth.