Originally appearing in "12 and a Half Angry Men", she is later named in "Carter and Tricia". In both cases, she berates her daughter for her perceived lack of success, despite being nominated for a local Emmy in the latter appearance. She is also disappointed in Tricia's lack in producing grandchildren to take care of her as she grows older. Her treatment of her daughter causes Peter to consider her upbringing as a cause for her own treatment of him when she became his "tiger mom" when she had an affair with Carter Pewterschmidt to uncover a news story.
Irene is voiced by Alex Borstein.