- The episode's title is a parody of the phrase "to come out of your shell".
- Stewie calls Lois "Casey Anthony" after she drops him, referring to the death of Caylee Anthony of which Casey was found not guilty despite intense public opinion of her guilt.[1]
- When Lois is trying to seduce Justin Bieber, she refers to herself as Mrs. Robinson, the woman that seduced Dustin Hoffman's character in the film, The Graduate, who Bieber has never heard of. When Bieber doesn't understand the reference, she refers to herself as Stifler's Mom, the woman that seduced Eddie Kaye Thomas' character in the film, American Pie, which Bieber still doesn't understand.
Previous Episode's References /// Lois Comes Out of Her Shell's References \\\ Next Episode's References
| << Season 10 | Family Guy Season 11 | Season 12 >> | |||||||||
| #01 | Into Fat Air | #09 | Space Cadet | #17 | Bigfat | ||||||
| #02 | Ratings Guy | #10 | Brian's Play | #18 | Total Recall | ||||||
| #03 | The Old Man and the Big 'C' | #11 | The Giggity Wife | #19 | Save the Clam | ||||||
| #04 | Yug Ylimaf | #12 | Valentine's Day in Quahog | #20 | Farmer Guy | ||||||
| #05 | Joe's Revenge | #13 | Chris Cross | #21 | Roads to Vegas | ||||||
| #06 | Lois Comes Out of Her Shell | #14 | Call Girl | #22 | No Country Club for Old Men | ||||||
| #07 | Friends Without Benefits | #15 | Turban Cowboy | ||||||||
| #08 | Jesus, Mary & Joseph | #16 | 12 and a Half Angry Men | ||||||||
| 200 Episodes Later | |||||||||||