• According to Seth MacFarlane, this is the last episode they were able to fully produce before the WGA went on strike. He has gone on record to say that he does not want FOX to hire anyone to finish any future episodes without his consent or involvement, saying "They could, but it would be unwise. Because I would be angry."
• For this episode, Ron Jones was nominated for a Primetime Emmy for "Outstanding Music Composition For A Series (original Dramatic Score)" in 2008.
• In the DVD version, Magic Johnson reappears and does a similar routine as he did in the "Blue Harvest" episode.
• When Lois and Peter switch bodies, Peter hums the Green Acres theme song while playing with Lois' breasts. This scene is deleted in some showings due to sexual references.
• Brian's car, the 2004 Toyota Prius, can be seen again in this episode.
• Although the car takes damage when Stewie shoots it up after nearly falling asleep, it is intact again when they reach CIA Headquarters.
• During the scene where Brian is driving Stewie to the CIA, when his gun goes off a total of 18 shots are heard. However, an M1911's magazine can only hold 7 shots.
• When the family is tied up, Peter suggests starting a rumor and then says that Rob Schneider picks up immigrants at Home Depot and makes them choke him in the shower (while he masturbates as mentioned in the dvd version). Later in the episode, this is revealed to actually be true.
• Willem Dafoe used to live under Stewie's cot. Stewie was scared of him.
• Agent Stan Smith and Deputy Director Avery Bullock are seen in the episode.
• While Lois normally wears a bra, she does not seem to wear one during Stewie's simulation.
• When Stewie bans straight-to-video Disney films, he complains about a fake movie titled "Aladdin 4: Jafar May Need Glasses". Also he says all milk must come from Hilary Swank's breasts. Then, at her mansion, they do a line from Total commercials.
• Stewie says he should have been this big when he practices for American Idol. It then cuts to him preforming "Lost In Your Eyes" for American Idol. He fails, and then exits the audition room giving a tear-felt speech typical of Idol rejects. Oddly, he uses a different accent during the speech.
• Stewie's entry number for American Idol was 09346.
• There are a couple of inconsistencies with Lois and Stewie's injuries during the fight scene: When Stewie is hit with the vase, his hands are bleeding. The blood disappears when he's playing with the pins from the grenades, but then re-appear when Lois surrenders. A scratch on Lois' left cheek mysteriously appears when she starts attacking with the pole. When Stewie starts using a flamethrower, the scratch has gone again.
• When Stewie attacks Lois with the flamethrower, he burns the American flag. This is a common anti-American symbol.
• When Stewie forces Brian to drive away from the house, the sound of the engine turning over can clearly be heard. However, because of the way that the engine is designed, a Toyota Prius has a silent ignition.
• During the battle between Lois and Stewie in the oval office, the presidential portraits can be seen on the wall. Bill Clinton appears naked in his portrait.
• Lois finishes off the chaingun's ammunition on George W. Bush's presidential portrait.
• The fat camp that Lois goes to work at is called Camp Putdownadaforka.
• There was originally going to be a musical number sung by Stewie while giving his televised address to the world, but it was cut for time. It appears on the DVD.
• Despite Stewie creating his own flag (his face against an orange and yellow background),the flag Lois is holding is American.
• In the armory, Lois is seen grabbing a light machine gun. However, she was not seen using it or having it, and her Mossberg was not seen with her or armed by her until she pulled it out when her micro Uzis and Stewie's Berettas were out of ammo. It was never fired.

Previous Episode's Notes/Trivia /// Lois Kills Stewie's Notes/Trivia \\\ Next Episode's Notes/Trivia