The Lone Ranger is a fictional character, a masked ex-Texas Ranger who, with his Indian companion Tonto, fights injustice in the American Old West.

When Brian claims that Peter's idea of getting sick intentionally is the worst idea ever in "Total Recall", Peter corrects him, noting that silver bullets were the worse idea ever. A cutaway gag shows the Lone Ranger's wife nagging him over the expense of the silver bullets.

After bringing the bad guys to justice in "Fighting Irish", the Lone Ranger invites Tonto out for drinks to celebrate but is turned down, with Tonto noting that he doesn't like hanging out with people from work.

Among the television shows featured in the background during Peter's introduction to ""Family Guy" Through the Years" is an image of The Lone Ranger.

The Lone Ranger is voiced by John Viener.