Lou Gehrig

Henry Louis "Lou" Gehrig (June 19, 1903 – June 2, 1941) was an American baseball player in the 1920s and 1930s, chiefly remembered for his prowess as a hitter, his consecutive games-played record and its subsequent longevity, and the pathos of his farewell from baseball at age 36, when he was stricken with a fatal neurological disease called amyotrophic lateral sclerosis (ALS).

Loka calls Chris Griffin a hero in "Jungle Love", causing Chris to demur that Lou Gehrig was a hero. Gehrig however, is shown falling prey to his own plot to unleash a nerve toxin on the world, ALS.

A vet confronts Brian about his drinking in "Once Bitten", ing "Lou Gehrig's Disease" as an example to introduce him to "Mickey Mantle's Disease".