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Mickey Mouse is a cartoon character and the official mascot of The Walt Disney Company. He was created by Walt Disney and Ub Iwerks at the Walt Disney Studios in 1928.
When Stewie and Brian first enter the house they mean to renovate in "Peter's Daughter", Brian says that you can hear "the mice humping in the walls,". Mickey Mouse's voice is heard from within the walls of the run-down house, enjoying sex.
Peter asks Brian to call him on his Mickey Mouse phone in "Dial Meg for Murder".
In "3 Acts of God", Brian notes that Peter thinks the family gets lucky every time they visit Disney World because Mickey Mouse happened to be there that day.
Mickey is parodied as a "Mickey Rabbit" balloon in the J.C. Penney's Thanksgiving Day Parade in "Turkey Guys".