The title of the episode is a parody to the animated film All Dogs go to Heaven.
Meg's rude behavior toward the atheist Brian upon her conversion to Christianity mirror's Cameron's influence on the casting and plotlines of Growing Pains after he became a born-again Christian; For instance, Cameron wanted and got series co-star Julie McCullough fired after learning she had posed in Playboy magazine.
The clip of God flying on a rocket sled is a reference to the 1980 Flash Gordon movie. Music is Queen's theme for same.
The bottle of Jägermeister says "What are you waiting for? Drink me! Do it!" and "Get to da choppah!" The quotes reference Dutch who was played by Arnold Schwarzenegger from the film Predator.
Wil Wheaton and Patrick Stewart's exchange at the McDonald's drive-thru is a direct quote from the movie Caddyshack.
Britney Spears is cursed by a Gypsy to become "thicker". This is a reference to the Stephen King book Thinner.