- Alex Borstein turned 36 the day this episode aired.
- In relation to the shows length in the real world, Bonnie has been pregnant for approximately ten years (1999-2009), not seven; the 'seven years' is a reference to seven seasons, however, instead of referring to real-time.
- Because of the Christian Bale tirade parody, this is the first episode whose original television broadcast feature on the DVD does not include the true original airing.
- Dr. Hartman delivers Susie Swanson, which adds to the list of types of medicine he practices. This list already includes gynecologist, family practitioner, pediatrician, and others.
- When Stewie throws down his guitar, it makes a "kabong!" sound like the El Kabong cartoons from Quick Draw McGraw.
- Brian's mocking of Stewie's music video in descriptive questions of increasing pitch is a running gag from previous episodes usually performed in relation to Brian's Writing Career.
- Scenes added following the original broadcast:
- Peter, Cleveland, and Quagmire have Mort Goldman pretend to be Joe to satisfy the real Joe's absence.
- Meg was animated into the scene where Stewie is introduced to Susie. Peter talks to Meg about having babies.
- At the beginning of the second act, Peter, Cleveland and Quagmire are seen watching Are You Smarter Than a Hispanic Maid?
- The Christian Bale joke was replaced by Quagmire talking about his fantasy about making movies with B+ movie stars and a not so expensive location and a cutaway showing a trailer for a movie with Jeff Bridges and Laura Linney entitled "Danger in Cincinnati" with Don LaFontaine's very last appearance on Family Guy before his death.
- After the music video, Brian says that it's the worst video he's ever seen and that he saw Peter frozen in "sex face", which is shown.
- Peter remarks how there's "more dough in here than a Swedish bakery" in response to the amount of money in the vault, with a gag about a Swedish bakery following that.
- Seamus's body is made entirely of wood, leaving Peter to question as to how he can still live.
- Quagmire and Peter distract the crowd at Carter's party by performing the Safety Dance by Men Without Hats.
- Stewie's sexual ambiguity is raised again in this episode. Stewie falls in love with newborn Susie Swanson which inspires him to write a song for her, then later compiles a music video for her based on Bryan Adams' song, "(Everything I Do), Do It For You." When Brian asks Stewie what Susie thought of his video, Stewie declares "I don't care about her anymore. I'm in love with Bryan Adams."
- The songs that Brian lists that are named after girls are
- "Rosanna" by Toto
- "Roxanne" by The Police
- "Michelle" by The Beatles
- "Allison" by Elvis Costello
- "Sara" by Starship
- "Angie" by The Rolling Stones
- "Brandy (You're a Fine Girl)" by Looking Glass
- "Mandy" by Barry Manilow
- "Gloria" by Umberto Tozzi
- "Cecilia" by Simon and Garfunkel
- "Maggie May" by Rod Stewart
- "Jessica" by The Allman Brothers Band
- "Nancy (With the Laughing Face)" by Frank Sinatra
- "Barbara Ann" by The Beach Boys
- "Billie Jean" by Michael Jackson
- "Layla" by Derek and the Dominoes
- "Lola" by The Kinks
- "Polly" by Nirvana
- "Helena" by The Misfits
- "Jenny from the Block" by Jennifer Lopez
- "Sherry" by The Four Seasons
- "Laura (What's He Got That I Ain't Got)" by Kenny Rogers
- "Wendy" by The Beach Boys
- "Maria" by Blondie
- "Peggy Sue" by Buddy Holly
- "Minnie the Moocher" by Cab Calloway and His Orchestra
- "Tracy" by Mogwai
- "Jean" by Oliver
- "Jane" by Barenaked Ladies
- "Mary Ann" by Black Lace
- "Eleanor Rigby" by The Beatles
- Peter says he has never watched a woman give birth, yet in "Emission Impossible" Peter delivers Carol Pewterschmidt's child and watched when Lois gave birth to Stewie in "Chitty Chitty Death Bang".
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#01 | Love, Blactually | #07 | Ocean's Three and a Half | #13 | Stew-Roids | |||
#02 | I Dream of Jesus | #08 | Family Gay | #14 | We Love You, Conrad | |||
#03 | Road to Germany | #09 | The Juice Is Loose | #15 | Three Kings | |||
#04 | Baby Not On Board | #10 | FOX-y Lady | #16 | Peter's Progress | |||
#05 | The Man with Two Brians | #11 | Not All Dogs Go To Heaven | |||||
#06 | Tales of a Third Grade Nothing | #12 | 420 |