Since Francis is not Peter's real father and therefore Peter is only a Griffin in name, not bloodline, Peter is not really related to Nate Griffin and is therefore not really part black. Although it is conceivable the Griffins and the McFinnigans share a common ancestor.
Peter mentions planning parties is worse than being stuck behind Robert Loggia at the airport. It then shows a scene with Robert Loggia spelling his name out slowly, using himself to describe each letter while spelling it for the clerk.
This is the last episode with Kevin Swanson, until he suddenly reappears after being reported as Missing in Action in "Thanksgiving".
Francis dies in this episode.
Lois appears as a dominatrix in Stewie’s fantasies.
The song Lois sings in the flashback to Meg’s last birthday party is “Sixteen Going On Seventeen” from The Sound of Music.
In her bedroom, Meg has a poster of American boy-band 'N Sync, which MacFarlane comments to be from "back when they were around".
As a birthday present, Meg receives a copy of the first season of the TV show Sister, Sister on DVD from Cleveland.
Excluding Ireland itself, Cork is the only real Irish area and county to be mentioned in the episode.
Peter tries to prove he is brave by saying that he managed to sit halfway through Failure to Launch.
David Tua is drawn by Stewie on the wall with a crayon to incite Lois to hit him.
Peter tries to entertain at Meg’s party by riding a unicycle. He first learned how to ride in “Peterotica”.
This episode also marks the second time in which Stewie’s interactions with the rest of the family are questioned; when he draws a picture of David Tua on the wall he says so out loud, and a moment later Lois expresses surprise that the picture Stewie drew looks somewhat like David Tua, as if she had no idea what Stewie had said. Stewie’s intelligence and capacity to talk has only been questioned once before, in the final scene of “E. Peterbus Unum”.
Quagmire tells a joke about a cocktail named grasshopper.
As reported in the DVD commentary; Stewie, upon discovering he liked being hit by Lois was supposed to sing a version of "I Want It Now!" from the film Willy Wonka and the Chocolate Factory. It was cut for time and has never been released due to licensing issues.