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Ponce de León Griffin is Peter Griffin's explorer ancestor, who searched for the Fountain of Youth.
Once he found it, he waded in it, and emerged from the water with the body of a baby, but his head, the only part of his body that didn't touch the water, stayed fully mature and grown. He sarcastically remarked that it was worth the eight and a half year boat ride, as seen in "The Perfect Castaway".