Quahog Books is the location of Peter Griffin's first book signing for his erotic novel in "Peterotica". When one of his fans compares him to Emily Brontë, he inquires about using her ass as a bongo drum. When she becomes offended, Peter simply signs her chest and moves on.

A larger Quahog Books is the site of Peter's debut of The Hopeful Squirrel 2 in "The Book of Joe" after his attitude causes Joe to abandon his book about a handicapped squirrel. To write the sequel, Peter enlists his friends, but the off-color material repels the children and their parents and Peter is fired by the publisher, Blake Walker.