Sherry and the Anus is a fictional sitcom seen in "The Story on Page One" by the Griffin family. The executive producer is Steven Marmel, the associate producer is Garrett Sheridan, the consulting producer is Danny Goldman, the co-producer is Matt Barker, and the executive story editor is Dave Weitzman.

The show revolves a girl named Sherry, who lives with her brother, whose body is only comprised of two butt cheeks. In one episode, Sherry enters Anus' room and asks him if he is still awake. She then asks him if it is alright to lie to keep a friend. In another episode Anus got a hamster stuck in his "mouth". Peter Griffin thought these episodes were the funniest of the series.